Capshaw was born in Columbia, Missouri, the daughter of actress and producer Kate Capshaw, and Robert Capshaw, a sales manager, marketing director, business executive, and high school principal. She is the stepdaughter of director Steven Spielberg. She graduated from Harvard-Westlake School in 1994 and Brown University in 1998 with an English degree. She then attended acting classes at the Royal Academy of Dramatic Arts (RADA) in London.
Capshaw married Christopher Gavigan on May 22, 2004 at her family's East Hampton estate. They have three children: son Luke Hudson Gavigan (born September 8, 2007) and daughters Eve Augusta Gavigan (born October 20, 2010) and Poppy James Gavigan (born June 20, 2012).
In the motion picture, Valentine, Capshaw played Dorothy Wheeler. In 2009, she became a regular on the medical drama Grey's Anatomy, reuniting with The Practice co-star Chyler Leigh and Valentine co-star Katherine Heigl. She was a recurring character in the fifth season, and was upgraded to series regular in the sixth.
|Odd Man Out||Aunt Jordan|
|2002||Minority Report||Officer Evanna|
|The Practice||Jamie Stringer|
|2003||"View from the Top"||Air Hostess|
|2005||Into the West||Rachel Wheeler|
|Thick and Thin||Mary|
|2007||The L Word||Nadia Karella|
|Blind Trust||Cassie Stewart|
|2009-present||Grey's Anatomy||Dr. Arizona Robbins|
|2010||One Angry Juror||Sarah Walsh|